Integrated Nanoplasmonic Biosensors for Protein Biomarkers

Jianjun Wei, Ph.D. | Professor of Nanoscience; Joint School of Nanoscience and Nanoengineering, University of North Carolina at Greensboro

Abstract: Nano-plasmonics, an emerging branch field of nanophotonics concerning properties of collective electronic excitations (surface plasmon, SP) in nanostructures of noble metals (e.g. silver and gold), has attracted intense attention due to its versatility for optical sensing and chip-based device integration. This talk covers our recent work developing a chip-based nanostructure metal film towards a nano-optofluidic device that incorporates an optical transmission sensing scheme with a function of size-dependent sample delivery in a single nanoscale unit. The device has been tested for delivery and detection of a couple disease related protein biomarkers (f-PSA for prostate cancer and anti-insulin antibody of type 1 diabetes (T1D)) as proof-of-concept, which offers a promise for development of a point-of-care technology in health care.

Bio: Dr. Jianjun Wei is currently a Professor of Nanoscience at the Joint school of Nanoscience and Nanoengineering (JSNN) at the University of North Carolina at Greensboro (UNCG). Dr. Wei joined JSNN/UNCG in 2013 as an Associate Professor of Nanosciece. Dr. Wei's research at JSNN has been supported by grants from NSF, NIH, NCBC, DOD and NC state funding. Prior to joining JSNN, he had worked in CFD Research Corporation in Huntsville, AL, from 2006 to 2013, and led as a Principal Scientist (PI or co-PI) for a number of BAA, SBIR/STTR Phase I, II, and III US government contracts primarily through NIH, NASA and DOD research grants. He obtained his Ph.D. in chemistry in 2004 at the University of Pittsburgh, followed with one-year postdoctoral fellowship at the same university.

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